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LABETALOL HYDROCHLORIDE

Names
Common NameLABETALOL HYDROCHLORIDE
Other NameLABETALOL HYDROCHLORIDE
Pharmacological GroupBETA BLOCKERS
Chemical Name5-[1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl]salicylamide hydrochloride; 2-Hydroxy-5-[1-hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl]benzamide hydrochloride
Chemical Group

Attributes

IndicationsContraindicationsPrescriber CautionsPatient Cautions
ToxicitySide EffectsLiver DiseaseRenal Failure
PregnancyLactationPharmacological ActionsDiagnostic Procedures
DrugsInteractions

Indications

Hypertension
Postmyocardial infarction syndrome
Angina pectoris
Hypertension complicating pregnancy/childbirth/puerperium
Paediatric use

Contraindications

Heart failure
Chronic obstructive airway disease
Asthma
Pulse rate - bradycardia
Complete atrioventricular block
Partial atrioventricular block
Sick sinus syndrome
Raynaud's syndrome
Chronic obstructive pulmonary disease
Chronic asthmatic bronchitis
Cardiogenic shock
Adverse reaction to betablockers
Adverse reaction to labetalol
Airways obstruction reversible
Beta blocker contraindicated
Betablocker allergy

Prescriber Cautions

Withdraw LABETALOL HYDROCHLORIDE gradually over at least a week
Caution in asthma or other obstructive pulmonary disease

Patient Cautions

See information on products containing LABETALOL HYDROCHLORIDE for specific advice for patients

Toxicity

- None Listed -

Side Effects

Postural hypotension - Uncommon
Acute hepatitis - Rare
Acute necrosis of liver - Rare
Angioneurotic oedema - Rare
Anti-nuclear factor positive - Rare
Bradycardia - Rare
Cardiac conduction disorders - Rare
Cramp - Rare
Dry eyes - Rare
Dyspnoea - Rare
Itching - Rare
Jaundice - Rare
Lichenified skin - Rare
Liver function tests abnormal - Rare
Lupus erythematosus - Rare
Oedema - Rare
Pyrexia - Rare
Rash - Rare
Toxic myopathy - Rare
Visual symptoms - Rare
Bronchospasm
Cold extremities
Confusion
Depression
Diarrhoea
Difficulty with micturition
Dizziness
Drug psychoses
Epigastric pain
Excessive sweating
Hallucinations
Headache
Heart failure
Inhibited male orgasm
Insomnia
Intermittent claudication
Malaise/lethargy
Nasal congestion
Nausea
Nightmares
Paraesthesia
Raynaud's phenomenon
Tingling sensation
Tired all the time
Tremor
Urinary retention
Vomiting

Liver Disease

Avoid LABETALOL HYDROCHLORIDE in liver disease
Hepatocellular injury reported

Renal Failure

May need reduced dose in renal failure
LABETALOL HYDROCHLORIDE - may reduce renal blood flow and reduce renal function in severe renal failure
LABETALOL HYDROCHLORIDE - higher serum concentrations after oral administration in severe renal failure

Pregnancy

LABETALOL HYDROCHLORIDE may retard intrauterine fetal growth
LABETALOL HYDROCHLORIDE causes neonatal bradycardia related to maternal dose
Avoid LABETALOL HYDROCHLORIDE in the 1st & 2nd TRIMESTER of pregnancy
Risk of neonatal hypoglycaemia with LABETALOL HYDROCHLORIDE

Lactation

Therapeutic doses of LABETALOL HYDROCHLORIDE unlikely to affect infant
LABETALOL HYDROCHLORIDE unlikely to be excreted in milk
Monitor infant
Possible toxicity from LABETALOL HYDROCHLORIDE due to beta-blocker effect

Pharmacological Actions

BETA ANTAGONIST action effect

Diagnostic Procedures

Urine 5-hydroxyindoleacetic acid high
Total bilirubin high
Creatine kinase low
Serum glucose low

Drugs containing LABETALOL HYDROCHLORIDE

LABETALOL 100mg tablets
LABETALOL 200mg tablets
LABETALOL 400mg tablets
LABROCOL 100mg tablets
LABROCOL 200mg tablets
LABROCOL 400mg tablets
TRANDATE 50mg tablets
TRANDATE 100mg tablets
TRANDATE 200mg tablets
TRANDATE 400mg tablets
TRANDATE 100mg/20mL injection
LABETALOL 50mg tablets
LABETALOL 100mg/20mL injection
Labetalol 200mg/5ml soln
Labetalol 200mg/5ml susp
Labetalol 25mg/5ml soln
Labetalol 25mg/5ml susp
Labetalol 50mg/5ml soln
Labetalol 50mg/5ml susp

Interacting Ingredients

ACETOHEXAMIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of ACETOHEXAMIDE. Moderate risk. Monitor
ADRENALINE
Likely interaction of LABETALOL HYDROCHLORIDE increasing the HYPERTENSIVE effect of ADRENALINE. Potential risk. Monitor
ADRENALINE [LOCAL]
Likely interaction of LABETALOL HYDROCHLORIDE increasing the HYPERTENSIVE effect of ADRENALINE [LOCAL]. Potential risk. Monitor
ALFUZOSIN HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOTENSIVE effect of ALFUZOSIN HYDROCHLORIDE. Potential risk. May need to avoid combination
ALMOTRIPTAN
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the VASOCONSTRICTOR effect of ALMOTRIPTAN. Potential risk. Avoid
AMINOPHYLLINE
Theoretical potential for LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of AMINOPHYLLINE. High risk. Avoid
AMIODARONE HYDROCHLORIDE
Likely interaction of LABETALOL HYDROCHLORIDE increasing the ARRHYTHMOGENIC effect of AMIODARONE HYDROCHLORIDE. Potential risk. May need to avoid combination
BAMBUTEROL HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of BAMBUTEROL HYDROCHLORIDE. High risk. Avoid
BECLOMETASONE [INHALED]
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of BECLOMETASONE [INHALED]. High risk. Avoid
BETAMETHASONE [INHALED]
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of BETAMETHASONE [INHALED]. High risk. Avoid
BIPHASIC INSULIN ASPART
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of BIPHASIC INSULIN ASPART. Moderate risk. Monitor
BIPHASIC INSULIN LISPRO
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of BIPHASIC INSULIN LISPRO. Moderate risk. Monitor
BUDESONIDE [INHALED]
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of BUDESONIDE [INHALED]. High risk. Avoid
BUFYLLINE
Theoretical potential for LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of BUFYLLINE. High risk. Avoid
CARBENOXOLONE
Likely interaction of CARBENOXOLONE reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Potential risk. Monitor
CARBENOXOLONE [MOUTH]
Likely interaction of CARBENOXOLONE [MOUTH] reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Potential risk. Monitor
CHLORPROMAZINE
Theoretical potential for CHLORPROMAZINE increasing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Potential risk. May need to avoid combination
CHLORPROPAMIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of CHLORPROPAMIDE. Moderate risk. Monitor
CHOLINE THEOPHYLLINATE
Theoretical potential for LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of CHOLINE THEOPHYLLINATE. High risk. Avoid
CIMETIDINE
Infrequent reports of CIMETIDINE increasing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. May need to avoid combination
CLONIDINE
Likely interaction of LABETALOL HYDROCHLORIDE increasing the HYPOTENSIVE effect of CLONIDINE. Potential risk. May need to avoid combination
CROMOGLICATE [INHALED]
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of CROMOGLICATE [INHALED]. High risk. Avoid
DARBEPOETIN ALFA
Theoretical potential for DARBEPOETIN ALFA reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
DEXIBUPROFEN
Infrequent reports of DEXIBUPROFEN reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
DIGITOXIN
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the NEGATIVE CHRONOTROPIC effect of DIGITOXIN. Moderate risk. May need to avoid combination
DIGOXIN
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the NEGATIVE CHRONOTROPIC effect of DIGOXIN. Moderate risk. May need to avoid combination
DIHYDROERGOTAMINE MESILATE
Infrequent reports of DIHYDROERGOTAMINE MESILATE increasing the VASOCONSTRICTOR effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
DILTIAZEM HYDROCHLORIDE
Infrequent reports of DILTIAZEM HYDROCHLORIDE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
DIPROPHYLLINE
Theoretical potential for LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of DIPROPHYLLINE. High risk. Avoid
DISOPYRAMIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the NEGATIVE CHRONOTROPIC effect of DISOPYRAMIDE. Moderate risk. May need to avoid combination
DISTIGMINE
Infrequent reports of DISTIGMINE increasing the NEGATIVE CHRONOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
EDROPHONIUM
Infrequent reports of EDROPHONIUM increasing the NEGATIVE CHRONOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
ELETRIPTAN
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the VASOCONSTRICTOR effect of ELETRIPTAN. Potential risk. Avoid
EPHEDRINE HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of EPHEDRINE HYDROCHLORIDE. High risk. Avoid
EPOETIN ALFA
Theoretical potential for EPOETIN ALFA reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
EPOETIN BETA
Theoretical potential for EPOETIN BETA reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
EPOETIN THETA
Theoretical potential for EPOETIN THETA reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
EPOETIN ZETA
Theoretical potential for EPOETIN ZETA reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
ERGOTAMINE TARTRATE
Infrequent reports of ERGOTAMINE TARTRATE increasing the VASOCONSTRICTOR effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
FELODIPINE
Infrequent reports of FELODIPINE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
FENOTEROL HYDROBROMIDE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of FENOTEROL HYDROBROMIDE. High risk. Avoid
FLECAINIDE ACETATE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the BETA ANTAGONIST effect of FLECAINIDE ACETATE. Moderate risk. Monitor
FLUTICASONE [INHALED]
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of FLUTICASONE [INHALED]. High risk. Avoid
FORMOTEROL
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of FORMOTEROL. High risk. Avoid
FROVATRIPTAN
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the VASOCONSTRICTOR effect of FROVATRIPTAN. Potential risk. Avoid
GALANTAMINE
Infrequent reports of GALANTAMINE increasing the NEGATIVE CHRONOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
GLIBENCLAMIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of GLIBENCLAMIDE. Moderate risk. Monitor
GLIBORNURIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of GLIBORNURIDE. Moderate risk. Monitor
GLICLAZIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of GLICLAZIDE. Moderate risk. Monitor
GLIMEPIRIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of GLIMEPIRIDE. Moderate risk. Monitor
GLIPIZIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of GLIPIZIDE. Moderate risk. Monitor
GLIQUIDONE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of GLIQUIDONE. Moderate risk. Monitor
GLYMIDINE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of GLYMIDINE. Moderate risk. Monitor
HUMAN INSULIN [INHALED]
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of HUMAN INSULIN [INHALED]. Moderate risk. Monitor
IBUPROFEN
Infrequent reports of IBUPROFEN reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
IBUPROFEN LYSINE
Infrequent reports of IBUPROFEN LYSINE reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
IMIPRAMINE
Likely interaction of LABETALOL HYDROCHLORIDE increasing the ANTIMUSCARINIC effect of IMIPRAMINE. Moderate risk. May need to avoid combination
INDACATEROL
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of INDACATEROL. High risk. Avoid
INDOMETACIN
Likely interaction of INDOMETACIN reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
INDOMETACIN [RECTUM]
Likely interaction of INDOMETACIN [RECTUM] reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
INSULIN ASPART
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of INSULIN ASPART. Moderate risk. Monitor
INSULIN DETEMIR
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of INSULIN DETEMIR. Moderate risk. Monitor
INSULIN GLARGINE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of INSULIN GLARGINE. Moderate risk. Monitor
INSULIN GLULISINE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of INSULIN GLULISINE. Moderate risk. Monitor
INSULIN LISPRO
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of INSULIN LISPRO. Moderate risk. Monitor
IODINE 123
Theoretical potential for LABETALOL HYDROCHLORIDE reducing the SERUM LEVEL of IODINE 123. Low risk. Monitor
IODINE 125
Theoretical potential for LABETALOL HYDROCHLORIDE reducing the SERUM LEVEL of IODINE 125. Low risk. Monitor
IODINE 131
Theoretical potential for LABETALOL HYDROCHLORIDE reducing the SERUM LEVEL of IODINE 131. Low risk. Monitor
ISOETARINE HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of ISOETARINE HYDROCHLORIDE. High risk. Avoid
ISOPRENALINE HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of ISOPRENALINE HYDROCHLORIDE. High risk. Avoid
ISOPRENALINE SULPHATE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of ISOPRENALINE SULPHATE. High risk. Avoid
ISRADIPINE
Infrequent reports of ISRADIPINE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
KETOTIFEN
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of KETOTIFEN. High risk. Avoid
LACIDIPINE
Infrequent reports of LACIDIPINE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
LERCANIDIPINE
Infrequent reports of LERCANIDIPINE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
LEVODOPA
Theoretical potential for LEVODOPA increasing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. May need to avoid combination
LEVOMEPROMAZINE
Theoretical potential for LEVOMEPROMAZINE increasing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Potential risk. May need to avoid combination
MEFLOQUINE HYDROCHLORIDE
Likely interaction of LABETALOL HYDROCHLORIDE increasing the ARRHYTHMOGENIC effect of MEFLOQUINE HYDROCHLORIDE. Moderate risk. May need to avoid combination
METFORMIN HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of METFORMIN HYDROCHLORIDE. Moderate risk. Monitor
METHOXY POLYETHYLENE GLYCOL EPOETIN BETA
Theoretical potential for METHOXY POLYETHYLENE GLYCOL EPOETIN BETA reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
METHYSERGIDE
Infrequent reports of METHYSERGIDE increasing the VASOCONSTRICTOR effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
MONTELUKAST
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of MONTELUKAST. High risk. Avoid
MOXISYLYTE
Likely interaction of LABETALOL HYDROCHLORIDE increasing the HYPOTENSIVE effect of MOXISYLYTE. Potential risk. May need to avoid combination
MOXONIDINE
Theoretical potential for LABETALOL HYDROCHLORIDE reducing the HYPOTENSIVE effect of MOXONIDINE. Moderate risk. May need to avoid combination
NAPROXEN
Infrequent reports of NAPROXEN reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
NAPROXEN SODIUM
Infrequent reports of NAPROXEN SODIUM reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
NAPROXEN [RECTUM]
Infrequent reports of NAPROXEN [RECTUM] reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
NEDOCROMIL SODIUM
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of NEDOCROMIL SODIUM. High risk. Avoid
NEOSTIGMINE
Infrequent reports of NEOSTIGMINE increasing the NEGATIVE CHRONOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
NICARDIPINE HYDROCHLORIDE
Infrequent reports of NICARDIPINE HYDROCHLORIDE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
NIFEDIPINE
Infrequent reports of NIFEDIPINE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
NIMODIPINE
Infrequent reports of NIMODIPINE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
NISOLDIPINE
Infrequent reports of NISOLDIPINE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
ORCIPRENALINE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of ORCIPRENALINE. High risk. Avoid
ORCIPRENALINE [INHALED]
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of ORCIPRENALINE [INHALED]. High risk. Avoid
PIRBUTEROL
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of PIRBUTEROL. High risk. Avoid
PIROXICAM
Likely interaction of PIROXICAM reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
PIROXICAM [RECTUM]
Likely interaction of PIROXICAM [RECTUM] reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
PIROXICAM-BETADEX
Likely interaction of PIROXICAM-BETADEX reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
PRAZOSIN HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOTENSIVE effect of PRAZOSIN HYDROCHLORIDE. Potential risk. May need to avoid combination
PRENYLAMINE
Likely interaction of LABETALOL HYDROCHLORIDE increasing the NEGATIVE INOTROPIC effect of PRENYLAMINE. High risk. Monitor
PYRIDOSTIGMINE BROMIDE
Infrequent reports of PYRIDOSTIGMINE BROMIDE increasing the NEGATIVE CHRONOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
QUINIDINE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the NEGATIVE CHRONOTROPIC effect of QUINIDINE. Moderate risk. May need to avoid combination
REPROTEROL HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of REPROTEROL HYDROCHLORIDE. High risk. Avoid
RIMITEROL HYDROBROMIDE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of RIMITEROL HYDROBROMIDE. High risk. Avoid
RITODRINE HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of RITODRINE HYDROCHLORIDE. High risk. Avoid
SALBUTAMOL
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of SALBUTAMOL. High risk. Avoid
SALBUTAMOL [INHALED]
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of SALBUTAMOL [INHALED]. High risk. Avoid
SALMETEROL XINAFOATE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of SALMETEROL XINAFOATE. High risk. Avoid
SULINDAC
Theoretical potential for SULINDAC reducing the HYPOTENSIVE effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
SUMATRIPTAN SUCCINATE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the VASOCONSTRICTOR effect of SUMATRIPTAN SUCCINATE. Potential risk. Avoid
TERAZOSIN HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOTENSIVE effect of TERAZOSIN HYDROCHLORIDE. Potential risk. May need to avoid combination
TERBUTALINE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of TERBUTALINE. High risk. Avoid
TERBUTALINE [INHALED]
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of TERBUTALINE [INHALED]. High risk. Avoid
THEOPHYLLINE
Theoretical potential for LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of THEOPHYLLINE. High risk. Avoid
TOLAZAMIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of TOLAZAMIDE. Moderate risk. Monitor
TOLBUTAMIDE
Infrequent reports of LABETALOL HYDROCHLORIDE increasing the HYPOGLYCAEMIC effect of TOLBUTAMIDE. Moderate risk. Monitor
TULOBUTEROL HYDROCHLORIDE
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of TULOBUTEROL HYDROCHLORIDE. High risk. Avoid
VERAPAMIL HYDROCHLORIDE
Infrequent reports of VERAPAMIL HYDROCHLORIDE increasing the NEGATIVE INOTROPIC effect of LABETALOL HYDROCHLORIDE. Moderate risk. Monitor
ZAFIRLUKAST
Infrequent reports of LABETALOL HYDROCHLORIDE reducing the BRONCHODILATOR effect of ZAFIRLUKAST. High risk. Avoid

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