Web based Drug Database (1.07 Linux)

BENZYDAMINE HYDROCHLORIDE

Names
Common Name	BENZYDAMINE HYDROCHLORIDE
Other Name	BENZYDAMINE HYDROCHLORIDE
Pharmacological Group	ANALGESICS - NON OPIOID
Chemical Name	3-(1-Benzyl-1H-indazol-3-yloxy)-NN-dimethylpropylamine hydrochloride
Chemical Group

Attributes

Indications	Contraindications	Prescriber Cautions	Patient Cautions
Toxicity	Side Effects	Liver Disease	Renal Failure
Pregnancy	Lactation	Pharmacological Actions	Diagnostic Procedures
Drugs	Interactions

Indications

Sore mouth
Sore throat
Streptococcal sore throat and scarlatina
Oral aphthae
Open wound in mouth
Open wound of pharynx
Paediatric use

Contraindications

Analgesic allergy
Adverse reaction to aromatic analgesics

Prescriber Cautions

Consult current official advice regarding BENZYDAMINE HYDROCHLORIDE

Patient Cautions

See information on products containing BENZYDAMINE HYDROCHLORIDE for specific advice for patients

Toxicity

- None Listed -

Side Effects

Burning or stinging - Uncommon
Numbness - Uncommon
Laryngeal spasm - Very Rare
Rash - Very Rare

Liver Disease

Avoid BENZYDAMINE HYDROCHLORIDE in severe liver disease
BENZYDAMINE HYDROCHLORIDE causes sodium and water retention in liver disease
BENZYDAMINE HYDROCHLORIDE - increased risk of gastrointestinal bleeding in liver disease

Renal Failure

Avoid BENZYDAMINE HYDROCHLORIDE if possible in mild renal failure
Manufacturer advises reduce dose of BENZYDAMINE HYDROCHLORIDE in renal failure
BENZYDAMINE HYDROCHLORIDE - reduces renal function in renal failure
BENZYDAMINE HYDROCHLORIDE - sodium and water retention in renal failure

Pregnancy

With regular doses of BENZYDAMINE HYDROCHLORIDE - increased risk of closure of fetal ductus arteriosus in utero & possible persistent pulmonary hypertension of the newborn
Delayed onset & increased duration of labour with increased blood loss
Avoid BENZYDAMINE HYDROCHLORIDE in the 1st TRIMESTER of pregnancy
Avoid BENZYDAMINE HYDROCHLORIDE in the 3rd TRIMESTER of pregnancy
Manufacturer advises toxicity of BENZYDAMINE HYDROCHLORIDE in pregnancy in animal studies

Lactation

Insufficient information available about BENZYDAMINE HYDROCHLORIDE in breast feeding. If treatment is essential alternative methods of feeding the infant should be considered

Pharmacological Actions

ANALGESIC effect
ANTIINFLAMMATORY effect
ANTIPYRETIC effect
CYCLOOXYGENASE INHIBITOR effect

Diagnostic Procedures

- None Listed -

Drugs containing BENZYDAMINE HYDROCHLORIDE

DIFFLAM 0.15% oral rinse 300mL
DIFFLAM 0.15% oral spray
DIFFLAM SORE THROAT rnse 200mL
BENZYDAMINE HCL 0.15% rinse
BENZYDAMINE HCL 0.15% spr
LOZAMINE throat loz lemon 20

Interacting Ingredients

AMINOPHYLLINE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of AMINOPHYLLINE. Moderate risk. Avoid
BAMBUTEROL HYDROCHLORIDE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of BAMBUTEROL HYDROCHLORIDE. Moderate risk. Avoid
BECLOMETASONE [INHALED]
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of BECLOMETASONE [INHALED]. Moderate risk. Avoid
BETAMETHASONE [INHALED]
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of BETAMETHASONE [INHALED]. Moderate risk. Avoid
BISMUTH CHELATE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of BISMUTH CHELATE. Moderate risk. Avoid
BUDESONIDE [INHALED]
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of BUDESONIDE [INHALED]. Moderate risk. Avoid
BUFYLLINE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of BUFYLLINE. Moderate risk. Avoid
CARBENOXOLONE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of CARBENOXOLONE. Moderate risk. Avoid
CHOLINE THEOPHYLLINATE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of CHOLINE THEOPHYLLINATE. Moderate risk. Avoid
CIMETIDINE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of CIMETIDINE. Moderate risk. Avoid
CLOPIDOGREL
Theoretical potential for BENZYDAMINE HYDROCHLORIDE increasing the PLATELET ANTAGONIST effect of CLOPIDOGREL. Moderate risk. May need to avoid combination
CROMOGLICATE [INHALED]
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of CROMOGLICATE [INHALED]. Moderate risk. Avoid
DEGLYCYRRHIZINISED LIQUORICE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of DEGLYCYRRHIZINISED LIQUORICE. Moderate risk. Avoid
DIPROPHYLLINE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of DIPROPHYLLINE. Moderate risk. Avoid
EPHEDRINE HYDROCHLORIDE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of EPHEDRINE HYDROCHLORIDE. Moderate risk. Avoid
ESOMEPRAZOLE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of ESOMEPRAZOLE. Moderate risk. Avoid
FAMOTIDINE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of FAMOTIDINE. Moderate risk. Avoid
FENOTEROL HYDROBROMIDE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of FENOTEROL HYDROBROMIDE. Moderate risk. Avoid
FLUTICASONE [INHALED]
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of FLUTICASONE [INHALED]. Moderate risk. Avoid
FORMOTEROL
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of FORMOTEROL. Moderate risk. Avoid
INDACATEROL
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of INDACATEROL. Moderate risk. Avoid
ISOETARINE HYDROCHLORIDE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of ISOETARINE HYDROCHLORIDE. Moderate risk. Avoid
ISOPRENALINE HYDROCHLORIDE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of ISOPRENALINE HYDROCHLORIDE. Moderate risk. Avoid
ISOPRENALINE SULPHATE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of ISOPRENALINE SULPHATE. Moderate risk. Avoid
KETOTIFEN
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of KETOTIFEN. Moderate risk. Avoid
LANSOPRAZOLE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of LANSOPRAZOLE. Moderate risk. Avoid
METHYLEPHEDRINE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of METHYLEPHEDRINE. Moderate risk. Avoid
MIFEPRISTONE
Theoretical potential for BENZYDAMINE HYDROCHLORIDE increasing the PROSTANERGIC effect of MIFEPRISTONE. Potential risk. Avoid
MONTELUKAST
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of MONTELUKAST. Moderate risk. Avoid
NEDOCROMIL SODIUM
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of NEDOCROMIL SODIUM. Moderate risk. Avoid
NIZATIDINE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of NIZATIDINE. Moderate risk. Avoid
OMEPRAZOLE [ORAL]
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of OMEPRAZOLE [ORAL]. Moderate risk. Avoid
OMEPRAZOLE [PARENTERAL]
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of OMEPRAZOLE [PARENTERAL]. Moderate risk. Avoid
ORCIPRENALINE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of ORCIPRENALINE. Moderate risk. Avoid
ORCIPRENALINE [INHALED]
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of ORCIPRENALINE [INHALED]. Moderate risk. Avoid
PANTOPRAZOLE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of PANTOPRAZOLE. Moderate risk. Avoid
PIRBUTEROL
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of PIRBUTEROL. Moderate risk. Avoid
RABEPRAZOLE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of RABEPRAZOLE. Moderate risk. Avoid
RANITIDINE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of RANITIDINE. Moderate risk. Avoid
RANITIDINE BISMUTH CITRATE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of RANITIDINE BISMUTH CITRATE. Moderate risk. Avoid
REPROTEROL HYDROCHLORIDE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of REPROTEROL HYDROCHLORIDE. Moderate risk. Avoid
RIMITEROL HYDROBROMIDE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of RIMITEROL HYDROBROMIDE. Moderate risk. Avoid
RITODRINE HYDROCHLORIDE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of RITODRINE HYDROCHLORIDE. Moderate risk. Avoid
SALBUTAMOL
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of SALBUTAMOL. Moderate risk. Avoid
SALBUTAMOL [INHALED]
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of SALBUTAMOL [INHALED]. Moderate risk. Avoid
SALMETEROL XINAFOATE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of SALMETEROL XINAFOATE. Moderate risk. Avoid
SUCRALFATE
Likely interaction of BENZYDAMINE HYDROCHLORIDE reducing the ULCER HEALING effect of SUCRALFATE. Moderate risk. Avoid
TERBUTALINE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of TERBUTALINE. Moderate risk. Avoid
TERBUTALINE [INHALED]
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of TERBUTALINE [INHALED]. Moderate risk. Avoid
THEOPHYLLINE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of THEOPHYLLINE. Moderate risk. Avoid
TULOBUTEROL HYDROCHLORIDE
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of TULOBUTEROL HYDROCHLORIDE. Moderate risk. Avoid
ZAFIRLUKAST
Infrequent reports of BENZYDAMINE HYDROCHLORIDE reducing the BRONCHODILATOR effect of ZAFIRLUKAST. Moderate risk. Avoid